Jak2 V617F Mutation Detection Qualitative Allele-Specific Amplification PCR Kit | \u06a9\u06cc\u062a \u062a\u0634\u062e\u06cc\u0635 \u062c\u0647\u0634 Jak2 V617F
\nJak2 V617F Mutation Detection Kit is a specialized product from Amir Peyvand Research and Development Company designed for the qualitative identification of the V617F point mutation in the JAK2 gene. This mutation is one of the most important molecular markers in myeloproliferative disorders such as Polycythemia Vera (PV), Essential Thrombocythemia (ET), and Primary Myelofibrosis (PMF).<\/p>\n
This kit uses the Allele-Specific Amplification PCR (AS-PCR) technique to provide a rapid, accurate, and reliable detection of the Jak2 V617F mutation in DNA samples.<\/p>\n
The kit includes all necessary components for performing 24 PCR reactions and is suitable for use in molecular diagnostic laboratories and research centers.<\/p>\n
Features:
\nHigh sensitivity and specificity for V617F mutation detection
\nAccurate and stable performance under various laboratory conditions
\nCustom design for both research and clinical applications
\nThe Jak2 V617F mutation is a signaling driver for Myeloproliferative Neoplasms (MPNs) associated with the proliferation and activation of three major myeloid lineages (erythroid, granulocytic, and megakaryoblastic). The V617F mutation is located on exon 14 of chromosome 9, resulting in the substitution of valine by phenylalanine at position 617. This causes hematopoietic cells to become more sensitive to factors such as erythropoietin and thrombopoietin.<\/p>\n
Jak2 V617F mutation holds significant diagnostic, prognostic, and therapeutic value. Quantitative detection of this mutation is useful for monitoring patients as a residual disease marker. With the Amir Peyvand Research and Development Company\u2019s kit, you can perform your molecular tests with confidence in result accuracy and time efficiency.<\/p>\n","protected":false},"excerpt":{"rendered":"
High sensitivity and specificity in detecting the V617F mutation
\nResults obtained in the shortest possible time (120 minutes)
\n100% diagnostic sensitivity and specificity
\nIncludes positive and negative controls to confirm the extraction process and PCR test<\/p>\n","protected":false},"featured_media":12998,"comment_status":"closed","ping_status":"closed","template":"","meta":{"inline_featured_image":false,"en_name":"","footnotes":""},"product_brand":[],"product_cat":[2485],"product_tag":[2655,2566,2654,2683,2565,2567,3115,3118,3110,3114,3113,3120,3674,3111,3112,3109,3116,3119,3117],"class_list":{"0":"post-13483","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-genomic-kits","7":"product_tag-amir-peyvand","8":"product_tag-amirpeyvand","9":"product_tag-ap-rad-2","10":"product_tag-ap-rad-3","11":"product_tag-ap-rad","12":"product_tag-aprad","13":"product_tag-jak2-mutation-detection-kit","14":"product_tag-jak2-mutation-test","15":"product_tag-jak2-v617f","16":"product_tag-jak2-v617f-conventional-pcr","17":"product_tag-jak2-v617f-detection","18":"product_tag-jak2-v617f-genetic-test-kit","19":"product_tag-jak2-v617f-kit-2","20":"product_tag-jak2-v617f-kit","21":"product_tag-jak2-v617f-mutation","22":"product_tag-jak2-v617f-mutation-detection-kit","23":"product_tag-jak2-v617f-mutation-kit","24":"product_tag-molecular-jak2-kit","25":"product_tag-pcr-conventional-jak2-v617f-kit","26":"pa_certificates-ivd","27":"pa_rxn-24r","29":"first","30":"instock","31":"sold-individually","32":"shipping-taxable","33":"product-type-simple"},"yoast_head":"\n