IMED License

BCR::ABL p210 Detection Kit

Features:

  • Performed in a one-step reaction (no need for cDNA synthesis)
  • 100% diagnostic sensitivity and specificity
  • Contains internal, positive, and negative controls to confirm the extraction process and PCR test
  • Results obtained in the shortest possible time (90 minutes)

Description

BCR::ABL p210 Detection rRT-PCR Kit | BCR::ABL p210 Detection Kit by rRT-PCR Method

The BCR::ABL p210 Detection rRT-PCR Kit is an advanced tool for the accurate and rapid detection of the BCR::ABL p210 gene in clinical samples. Utilizing Real-Time Reverse Transcription PCR (rRT-PCR) technology, this kit enables the identification of aberrations and mutations associated with hematologic malignancies such as Chronic Myeloid Leukemia (CML) with high sensitivity and specificity. The BCR::ABL p210 Detection rRT-PCR Kit from ap-rad is designed and manufactured for the rapid, sensitive, and specific detection of the BCR::ABL p210 fusion.

The t(9;22) BCR::ABL chromosomal translocation is observed in patients with Chronic Myeloid Leukemia (CML) and some cases of B-cell Acute Lymphoblastic Leukemia (Ph+ ALL). This fusion is located on the derivative chromosome 22q11 and produces a chimeric mRNA transcript that drives uncontrolled cell proliferation. Typically, e13-a2 or e14-a2 transcripts are produced, leading to the generation of a 210 kilodalton protein (p210).

Key Features of the Kit:

  • High Sensitivity: Detects the lowest amount of target RNA in clinical samples.
  • Fast and Reliable Results: Suitable for use in molecular diagnostic laboratories.
  • Easy to Use: Includes all necessary materials for performing rRT-PCR without the need for additional equipment.
  • Standard Quality: Manufactured according to international standards for molecular testing.

This kit is ideal for clinical research, patient treatment monitoring, and the timely diagnosis of BCR::ABL-related diseases, helping laboratories make more accurate treatment decisions with confidence and speed.

ap-rad, a provider of molecular diagnostic kits with the highest quality standards, is ready to collaborate with laboratories across the country.

اطلاعات کیت
Description Real-Time Amplification Kit with Genomic RNA Extraction of Specimen
Method Real-Time
Type Qualitative
Regulatory Status IUO
Storage & Transfer Condition (˚C) 20-
Number of Reactions 25
Controls Positive & Negative
Applicable Instruments All Type of Real-Time PCR Machines with FAM and JOE Channels
Result Display Time 1.5hours
Validated Specimens Peripheral Blood
Bone Marrow Aspirate
Sample Volume 2µL
Analytical Sensitivity (Copy/µL)s 0.5Copy/µL
Analytical Specificity 100%
Clinical Sensitivity 100%
Clinical Specificity 100%
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