Description
31 HPV Genotypes Real Time PCR Kit
HPV (Human Papillomavirus) is a DNA virus recognized as one of the most important causes of sexually transmitted diseases and can cause various skin and mucosal disorders in humans. The clinical manifestations of this virus depend significantly on the anatomical site of the lesion and the type of HPV genotype involved, ranging from asymptomatic lesions to precancerous changes and cancer. To date, over 200 different HPV genotypes have been identified, with more than 40 types infecting the human genital tract. Among these, approximately one-third of genotypes are associated with cervical cancer and anal neoplasia, playing a significant role in the epidemiology of genital diseases and cancer screening.
Anogenital HPV viruses are divided into two main groups:
- High-risk HPV genotypes: This group has high oncogenic potential and can cause precancerous lesions and invasive cancers such as cervical cancer by damaging cell proliferation control systems. The most common high-risk genotypes include 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, and 68.
- Low-risk HPV genotypes: This group is typically associated with benign, asymptomatic lesions such as genital warts and has low oncogenic risk. The most common low-risk genotypes include 6 and 11, as well as 40, 42, 43, 44, 54, 55, 61, 67, 74, 81, 83, 84, and 91.
Considering the high importance of accurate detection of HPV genotypes in cancer screening and clinical patient management, ap-rad has designed and manufactured the 31 HPV Genotypes Real-Time PCR Kit. This kit is capable of rapid, sensitive, and specific detection of 31 common HPV genotypes, including 16 high-risk genotypes and 15 low-risk genotypes. The use of this kit enables timely screening, identification of at-risk patients, and preventive treatment management, making it an ideal tool for molecular diagnostic laboratories, public health centers, and HPV epidemiological research.
