IMED License

Fungi Molecular Detection Kit (Fungiplex)

Features:

  • Results obtained in the shortest possible time (150 minutes)
  • Differential detection of Mucor, Candida albicans, Candida glabrata, and Aspergillus species
  • 100% diagnostic sensitivity and specificity
  • Contains internal, positive, and negative controls to confirm the extraction process and PCR test

Description

Fungi Molecular Detection Kit (Fungiplex PCR Kit)

Fungi are a large group of eukaryotic organisms that include molds and yeasts. These organisms are dispersed through the environment and air by transmitting their spores and can grow under suitable conditions. Many fungi naturally reside in the human body, but when overgrown, especially in individuals with immunodeficiency, they can cause fungal infections.

Fungal infections can occur on the skin, nails, and mucous membranes, referred to as superficial or mucocutaneous infections. They may also cause disease beneath the skin (subcutaneous infections) or in internal organs such as the lungs, brain, and heart (deep infections).

Among various fungal species, some have greater clinical significance in pathogenesis:

  • Mucor, the causative agent of Mucormycosis, is a rapidly progressing and life-threatening infection.
  • Candida albicans and Candida glabrata, causative agents of Candidiasis and invasive Candidiasis, can involve various body systems.
  • Aspergillus species, causative agents of Aspergillosis, primarily affect the lungs and severely immunocompromised patients.

Considering the importance of rapid and accurate detection of these pathogenic species, ap-rad has designed and manufactured the Fungiplex PCR Kit. This kit is developed for the rapid, sensitive, and specific identification of ITS sequences in fungi, including Mucor, Candida albicans, Candida glabrata, and Aspergillus species. The use of this kit enables timely diagnosis, screening of at-risk patients, and appropriate treatment management, making it an ideal tool for molecular diagnostic laboratories, healthcare centers, and epidemiological research.

اطلاعات کیت
Description Conventional Amplification Kit with Fungal DNA Extraction of Specimen
Method Real-Time
Type Qualitative
Regulatory Status RUO
Storage & Transfer Condition (˚C) 20-
Number of Reactions 25 & 50
Controls Positive & Negative
Applicable Instruments All Type of Thermal Cycler PCR Machines
Result Display Time 2.5hours
Validated Specimens Sputum
BAL
Sample Volume 10µL
Analytical Sensitivity (Copy/µL)s 5.4 (ITS), 8 (Mucor), 7.1 (Candida albicans), 9.2 (Candida glabrata) and 4.25 (Aspergillus species) Copy/µL
Analytical Specificity 100%
Clinical Sensitivity 100%
Clinical Specificity 100%
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Detection Capability:

  • Mycoplasma (M. hominis / M. genitalium)
  • Chlamydia trachomatis
  • Ureaplasma (U. urealyticum / U. parvum)
  • Herpes simplex virus 2 (HSV-2)
  • Herpes simplex virus 1 (HSV-1)
  • Trichomonas vaginalis
  • Treponema pallidum
  • Neisseria gonorrhoeae
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Detection of 10 bacteria including:

  • Streptococcus pneumoniae
  • Staphylococcus aureus
  • Haemophilus influenzae
  • Mycoplasma pneumoniae
  • Chlamydia pneumoniae
  • Legionella pneumophila
  • Pseudomonas aeruginosa
  • Klebsiella pneumoniae
  • Bordetella pertussis
  • Bordetella parapertussis

and one fungus including:

  • Pneumocystis jirovecii
6-Plex Bacterial Meningitis
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6-Plex Bacterial Meningitis-AP6PBMRK1 includes:

  • Streptococcus pneumoniae
  • Neisseria meningitidis
  • Haemophilus influenzae
  • Escherichia coli
  • Listeria monocytogenes
  • Streptococcus agalactiae (GBS)
5 Bacterial Pneumonia Detection Real Time PCR Kit
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Detection capability for five pneumonia bacteria including:

  • Streptococcus pneumoniae
  • Staphylococcus aureus
  • Haemophilus influenzae
  • Klebsiella pneumoniae
  • Pseudomonas aeruginosa
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  • Results obtained in the shortest possible time (2 hours)
  • 100% diagnostic sensitivity and specificity
  • Performed in a one-step reaction (no need for cDNA synthesis)
  • Contains internal, positive, and negative controls to confirm the extraction process and PCR test
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  • Results obtained in the shortest possible time (2 hours)
  • 100% diagnostic sensitivity and specificity
  • Performed in a one-step reaction (no need for cDNA synthesis)
  • Contains internal, positive, and negative controls to confirm the extraction process and PCR test