Description
Treponema pallidum Real-Time PCR Kit
Treponema pallidum is a double-stranded DNA bacterium belonging to the Spirochaetaceae family and is the causative agent of syphilis. This bacterium, with its high motility and ability to adhere to extracellular matrix components, can rapidly invade various body tissues and facilitate infection spread.
Syphilis is a chronic, multi-stage infection primarily transmitted through sexual contact and can also be transmitted from mother to child during pregnancy or childbirth. The disease consists of three stages:
- Primary syphilis: Sores called chancres appear at the infection site.
- Secondary syphilis: Associated with rashes and mucous membrane lesions, may cause cold-like symptoms.
- Latent and late syphilis: If untreated, the disease progresses to a latent stage with no apparent symptoms and may later develop into late syphilis years afterward, causing severe complications in the heart, brain, and other vital organs.
Annually, approximately 8 million new cases of syphilis are reported worldwide. Early diagnosis and timely treatment are essential to prevent severe disease consequences.
Diagnosis of this infection is typically performed using serological tests, but the Real-Time PCR technique, due to its speed, sensitivity, and high accuracy, is particularly useful for diagnosing congenital syphilis, neurosyphilis, and primary syphilis.
With the aim of rapid, sensitive, and specific detection of Treponema pallidum and its differentiation from other bacteria in human samples, ap-rad has designed and manufactured the Treponema pallidum Real-Time PCR Kit. This kit is an effective tool for molecular diagnostic laboratories, healthcare centers, and clinical research, enabling accurate and timely diagnosis of syphilis.
